21C Museum Hotel Louisville Exterior photo The photo shows a sunny street scene in a city, featuring a prominent golden statue of a muscular male figure, likely a depiction of the Greek god Hercules or a similar mythological character. The statue stands on a light-colored pedestal in the midd21C Museum Hotel Louisville Exterior photo This is an image of a large, modern art gallery space.

The room has a polished, grey concrete floor and white walls, giving it a clean and minimalist aesthetic. In the center-left, there is a prominent, contemporary architectural feature: a grey sta21C Museum Hotel Louisville Exterior photo This is an image of a modern, stylish event space or meeting room set up for a function or conference.

**Here's a detailed description:**

*   **Setting:** The room has an industrial chic aesthetic, featuring an exposed, dark wooden beam ceiling. Th

21C MUSEUM HOTEL LOUISVILLE

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Check rooms and rates
From$167 /night
Check-in
10Jun
Check-out
11Jun
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

700 West Main Street, Louisville, 40202
-
Steps from the Muhammad Ali Center
Great
8.8
9.3
/10
4.6
4.5
/5

21C Museum Hotel Louisville: A Contemporary Stay with Art-Centric Experience

Amenities

21C Museum Hotel Louisville offers a unique blend of hospitality and contemporary art. The hotel features a 9,000 square foot contemporary art museum with rotating exhibitions and installations. Guests can explore the art exhibits throughout the hotel, allowing for an immersive experience.

Rooms

The hotel provides 91 guest rooms, each designed with custom furniture and artwork from the hotel's collection. A designated 21C suite is available, featuring an expansive floor plan and premium amenities. Rooms include rainfall showers and Malin + Goetz bath products, ensuring a comfortable stay.

Location

Situated in downtown Louisville, the hotel is conveniently located near attractions like the Louisville Slugger Museum and the Muhammad Ali Center. The vibrant location enables easy access to local dining and entertainment options. Guests can explore the energetic streets, showcasing the culture and charm of Louisville.

Dining

The hotel features Proof on Main, a restaurant that emphasizes local ingredients and curated wines. Diners can enjoy a menu inspired by regional flavors, accompanied by a robust collection of Kentucky Bourbon. The location offers an engaging dining experience within an artistic setting.

Business Facilities

21C Museum Hotel Louisville includes versatile meeting spaces for corporate gatherings and events. The largest space accommodates up to 100 guests, equipped with modern technology for presentations. The hotel's unique artistic atmosphere can stimulate creative discussions during meetings.

Highlights

Amenities: 9,000 square foot contemporary art museum

Rooms: 91 guest rooms with custom furniture

Dining: Proof on Main with local ingredients

Business: Versatile meeting spaces with modern technology

“The downtown location is a clear win, especially for those keen on exploring Louisville's bourbon heritage and museum row. What truly sets this place apart, however, is the seamless integration of contemporary art and a vibrant atmosphere, making it more than just a place to stay. The staff's genuine warmth and the dining experience contribute significantly to its memorable character.”
Hotel logo
James DavidEditor-in-Chief at Uskentucky

Select your room type

21C Museum Hotel Louisville offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
  • Room Balcony
    2 persons
    29 sq. feet
    1 King-size bed
    Air conditioning
    Balcony
  • Deluxe King Room
    2 persons
    31 sq. feet
    1 King-size bed
    Air conditioning
    Heating
  • Corner Suite
    2 persons
    61 sq. feet
    1 King-size bed
    Air conditioning
    Bathtub
Show all rooms

Price and Room Availability Calendar

Check availability and prices for your dates now!
June 2026 - June 2027
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Check-in/ Check-out

Facilities

21C Museum Hotel Louisville offers amenities for your comfortable stay and unforgettable experiences
Facilities: Great
8.9/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers

Sports & Fitness

  • Fitness centre
  • Yoga class

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Outdoor dining area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Spa & wellness centre
  • Sauna
  • Turkish bath
  • Steam room
  • Full body massage

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Patio
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV

Room decor

  • Carpeted floor
Show more

Dining Onsite

At 21C Museum Hotel Louisville, the onsite dining option beautifully merges contemporary American cuisine with a creative atmosphere. Guests can indulge in memorable meals at Proof on Main while enjoying unique events that celebrate local distillers and the rich flavors of the region.
21C Museum Hotel Louisville Restaurant photo The photo shows a brightly colored, unique bedroom with a striking geometric ceiling. The ceiling is constructed from numerous triangular panels, each covered in a different vibrant fabric – blues, greens, reds, oranges, yellows, pinks, and purples.
21C Museum Hotel Louisville Restaurant photo The photo shows the interior of a restaurant with a whimsical and artistic decor. The walls are a mix of exposed brick and a large, colorful wallpaper depicting a vintage floral pattern. Numerous framed pictures and artwork of varying sizes and style
21C Museum Hotel Louisville Restaurant photo The photo shows a brightly lit dining area with a whimsical and eclectic decor. The walls are covered in a busy, patterned wallpaper featuring a mix of floral and figural designs in warm, muted tones. 

Numerous framed artworks of varying sizes and s

Proof on Main

American
Ambiance
Modern and inviting, featuring contemporary art pieces throughout the space, creating a vibrant dining atmosphere.
Key Offerings
The menu highlights regional dishes and ingredients, complemented by an impressive selection of craft cocktails. Guests can partake in special events like the Fork & Bottle dinner series, which showcases renowned guest distillers, and the annual Hog & Barrel dinner featuring Pappy Van Winkle.
Reservation
Recommended for special events.
Hours vary.

21C Museum Hotel Louisville Location

700 West Main Street, Louisville, 40202
Explore Louisville
Local Experiences
  • Top Attractions
  • Activities
  • Dining
  • Entertainment
Kentucky Science Center
2 minutes walking
Interactive exhibits and a 4D theater highlight science education. Great for families and offers free admission on select days.
Louisville Slugger Museum & Bat Factory
3 minutes walking
Home of the famous baseball bats, featuring guided tours and interactive displays. A must-see for sports enthusiasts.
Muhammad Ali Center
4 minutes walking
A tribute to the life and legacy of Muhammad Ali, showcasing his journey and impact on the world through engaging exhibitions.
KFC Yum Center
9 minutes walking
A premier venue for sports and concerts, hosting major events year-round, including basketball games and live performances.
Waterfront Park
17 minutes walking
Scenic park with walking trails and playgrounds, perfect for relaxation. Ideal for picnics and outdoor family activities.
Angel's Envy Distillery Tour
19 minutes walking
Tour the distillery where Angel's Envy bourbon is made, including tastings. Reservations recommended for a guided experience.
Biking on Big Four Bridge
25 minutes walking
Biking or walking across this iconic bridge offers stunning views of the river and city skyline. Bike rentals available nearby.
Proof On Main
1 minute walking
Artful ambiance with locally sourced ingredients. Known for its modern American cuisine and curated bourbon selection.
Mussel & Burger Bar Downtown
1 minute walking
Casual setting with gourmet burgers and fresh mussels. Offers vegetarian options and a vibrant beer selection.
Bristol Bar & Grille
2 minutes walking
Local favorites in a friendly atmosphere. Known for farm-to-table dishes and a great selection of local wines.
Fourth Street Live!
10 minutes walking
Lively entertainment district featuring bars, restaurants, and live music events. Ideal for nightlife and family-friendly activities.
KFC Yum Center Events
9 minutes walking
Home to concerts and sporting events, offering an exciting atmosphere. Check the schedule for family-friendly shows.
Getting around
  • City Centre
    Louisville 23 min  ·  1.2 mi
  • Airports
    Louisville (SDF) 18 min  ·  7.4 mi
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
Wireless internet is available in the entire hotel for free.
Children & extra beds
Maximum capacity of extra beds in a room is 1. 
Pets
Pets are allowed on request.
Year renovated:
2006
Number of floors:
4
Number of rooms:
96
Former name
21c Museum Hotel

Reviews and Ratings

Feedback about 21C Museum Hotel Louisville from previous guests about their experience.
Review score
Based on 429 verified reviews
9.0 /10
Perfect
88 %
Recommend
Breakfast
2.5/10
Cleanliness
9.1/10
Comfort
9.3/10
Facilities
8.9/10
Free WiFi
10.0/10
Location
9.4/10
Paid Wi-Fi
7.5/10
Staff
9.0/10
Value for money
8.1/10
Pros
Unique museum concept
Comfortable beds
Convenient valet parking
Friendly staff
Pleasant bar atmosphere
Cons
Thin walls
Underwhelming spa facilities
Inconsistent housekeeping
Guest reviews
based on 1899 reviews
4.5/5
based on 185 reviews
8.8/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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